HAMILTON, James. OBSERVATIONS ON THE UTILITY AND ADMINISTRATION OF PURGATIVE MEDICINES IN SEVERAL DISEASES. Philadelphia: Benjamin Johnson, and Collins and Perkins, New York, 1809. First American, from the second Edinburgh edition. 274p. 12mo. Contemporary full leather binding with gilt lettered spine label. The binding is scuffed and soiled, and the joints are cracked. A good copy. (Shaw & Shoemaker 17701).